genomic messages how the evolving science of genetics affects our health families and future

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Genomic Messages

Author : George Annas
ISBN : 9780062228277
Genre : Health & Fitness
File Size : 59. 75 MB
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Two leaders in the field of genetics—a bioethicist-health lawyer and an obstetrician-gynecologist geneticist—answer the most pressing questions about the application of new genetics to our universal medicine and what personalized medicine means for individual healthcare. Breakthroughs in genetic research are changing modern medicine and pharmaceuticals. But what are these changes and how do they affect our individual care? Genomic Messages examines these groundbreaking changes and the questions they raise: What kind of specific medical innovation do we have to look forward to now and tomorrow? How will this “flood” of genetic messages change our lives, our interaction with our physicians and our healthcare system? Groundbreaking and provocative, Genomic Messages fuses the often conflicting worlds of medicine and law to provide information and insight that will impact the health choices of every one of us, from how medicine is practiced to concepts of privacy, confidentiality, and informed consent. Ultimately, it reveals how genetic information is changing how we think about ourselves, our health, and our future.

Making Sense Of Genes

Author : Kostas Kampourakis
ISBN : 9781108210676
Genre : Science
File Size : 81. 60 MB
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What are genes? What do genes do? These seemingly simple questions are in fact challenging to answer accurately. As a result, there are widespread misunderstandings and over-simplistic answers, which lead to common conceptions widely portrayed in the media, such as the existence of a gene 'for' a particular characteristic or disease. In reality, the DNA we inherit interacts continuously with the environment and functions differently as we age. What our parents hand down to us is just the beginning of our life story. This comprehensive book analyses and explains the gene concept, combining philosophical, historical, psychological and educational perspectives with current research in genetics and genomics. It summarises what we currently know and do not know about genes and the potential impact of genetics on all our lives. Making Sense of Genes is an accessible but rigorous introduction to contemporary genetics concepts for non-experts, undergraduate students, teachers and healthcare professionals.

What We Talk About When We Talk About Clone Club

Author : Gregory E. Pence
ISBN : 9781942952350
Genre : Performing Arts
File Size : 83. 66 MB
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What is the real-world history and science of human cloning, and does Orphan Black get it right? Can you “own” a person—even a cloned one? How can Sarah Manning be straight, Cosima gay, and Tony trans? Cult hit sci-fi show Orphan Black doesn’t just entertain—it also raises fascinating questions about human cloning, its ethics, and its impact on personal identity. In What We Talk About When We Talk About Clone Club: Bioethics and Philosophy in Orphan Black, prominent bioethicist Gregory E. Pence violates Clone Club’s first rule to take us deeper into the show and its connections to the real world, including: Widespread myths about human clones (and Orphan Black’s rejection of them) Our ugly history of eugenics The ethics of human experimentation, by way of Projects Castor and Leda What we can learn about clones and identity from twin studies and tensions among Orphan Black’s clone “sisters” Kendall Malone and other genetic anomalies The brave new world of genetic enhancement and clonal dynasties, and how Helena and Kira Manning fit in In the process, What We Talk About When We Talk About Clone Club reveals why Orphan Black is some of today’s most engaging and thought-provoking television.

Biocode

Author : Dawn Field
ISBN : 9780199687756
Genre : Science
File Size : 52. 18 MB
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The living world runs on genomic software - what Dawn Field and Neil Davies call the 'biocode' - the sum of all DNA on Earth. In Biocode, they tell the story of a new age of scientific discovery: the growing global effort to read and map the biocode, and what that might mean for the future. The structure of DNA was identified in 1953, and the whole human genome was mapped by 2003. Since then the new field of genomics has mushroomed and is now operating on an industrial scale. Genomes can now be sequenced rapidly and increasingly cheaply. The genomes of large numbers of organisms from mammals to microbes, have been mapped. Getting your genome sequenced is becoming affordable for many. You too can check paternity, find out where your ancestors came from, or whether you are at risk of some diseases. Some check out the pedigree of their pets, while others turn genomes into art. A stray hair is enough to crudely reconstruct the face of the owner. From reading to constructing: the first steps to creating artificial life have already been taken. Some may find the rapidity of developments, and the potential for misuse, alarming. But they also open up unprecedented possibilities. The ability to read DNA has changed how we view ourselves and understand our place in nature. From the largest oceans, to the insides of our guts, we are able to explore the biosphere as never before, from the genome up. Sequencing technology has made the invisible world of microbes visible, and biodiversity genomics is revealing whole new worlds within us and without. The findings are transformational: we are all ecosystems now. Already the first efforts at 'barcoding' entire ecological communities and creating 'genomic observatories' have begun. The future, the authors argue, will involve biocoding the entire planet.

Building Genetic Medicine

Author : Shobita Parthasarathy
ISBN : 9780262250092
Genre : Medical
File Size : 25. 85 MB
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In Building Genetic Medicine, Shobita Parthasarathy shows how, even in an era of globalization, national context is playing an important role in the development and use of genetic technologies. Focusing on the development and deployment of genetic testing for breast and ovarian cancer (known as BRCA testing) in the United States and Britain, Parthasarathy develops a comparative analysis framework in order to investigate how national "toolkits" shape both regulations and the architectures of technologies and uses this framework to assess the implications of new genetic technologies. Parthasarathy argues that differences in the American and British approaches to health care and commercialization of research led to the establishment of different BRCA services in the two countries. In Britain, the technology was available through the National Health Service as an integrated program of counseling and laboratory analysis, and was viewed as a potentially cost-effective form of preventive care. In the United States, although BRCA testing was initially offered by a number of providers, one company eventually became the sole provider of a test available to consumers on demand. Parthasarathy draws lessons for the future of genetic medicine from these cross-national differences, and discusses the ways in which comparative case studies can inform policy-making efforts in science and technology.

Introduction To Genomics

Author : Arthur Lesk
ISBN : 9780199564354
Genre : Medical
File Size : 52. 25 MB
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Our genome is the blueprint to our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism. But how do we identify the genes that make up our genome? How do we determine their function? And how do different genes form the regulatory networks that direct the processes of life? Introduction to Genomics is a fascinating insight into what can be revealed from the study of genomes: how organisms differ or match; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genome structure and function means in terms of our future health and wellbeing. Thoroughly revised and brought up to date, the second edition features: * Coverage of the latest techniques and developments in the field * Rich pedagogy: End-of-chapter exercises, web-based problems ("weblems"), and lab assignments; "Special Topic" boxes; engaging case studies new "Ethics" boxes exploring the ethical issues surrounding the study of genomics; highlighted key terms; and an end-of-book glossary * A larger format provides greater clarity to the text and accompanying figures * Five new chapters, including one dedicated to metabolomics * An updated Companion Website (www.oup.com/uk/orc/bin/9780199564354) offering a range of resources, including figures from the book in electronic format, answers to end-of-chapter exercises, hints to end-of-chapter problems, a guided tour of web sites in genomics, and rotating figures The field of genomics is enabling us to analyze life in more detail than ever before; and Introduction to Genomics tackles this conceptually challenging--and fascinating--subject in a clear, lucid way.

Future Humans

Author : Scott Solomon
ISBN : 9780300208719
Genre : Science
File Size : 27. 33 MB
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Are humans still subject to the forces of evolution? An evolutionary biologist provides surprising insights into the future of Homo sapiens In this intriguing book, evolutionary biologist Scott Solomon draws on the explosion of discoveries in recent years to examine the future evolution of our species. Combining knowledge of our past with current trends, Solomon offers convincing evidence that evolutionary forces still affect us today. But how will modernization--including longer lifespans, changing diets, global travel, and widespread use of medicine and contraceptives--affect our evolutionary future? Solomon presents an entertaining and accessible review of the latest research on human evolution in modern times, drawing on fields from genomics to medicine and the study of our microbiome. Surprising insights, on topics ranging from the rise of online dating and Cesarean sections to the spread of diseases such as HIV and Ebola, suggest that we are entering a new phase in human evolutionary history--one that makes the future less predictable and more interesting than ever before.

The Selfish Gene

Author : Richard Dawkins
ISBN : 0192860925
Genre : Literary Criticism
File Size : 64. 41 MB
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An ethologist shows man to be a gene machine whose world is one of savage competition and deceit

The Gene

Author : Siddhartha Mukherjee
ISBN : 9781476733531
Genre : Medical
File Size : 43. 57 MB
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THE #1 NEW YORK TIMES BESTSELLER A New York Times Notable Book A Washington Post and Seattle Times Best Book of the Year From the Pulitzer Prize-winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).

The Genetics Of Health

Author : Sharad P. Paul
ISBN : 9781501155413
Genre : Family & Relationships
File Size : 47. 96 MB
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"SHARAD P. PAUL, MD, is starting a health RxEvolution. He argues it's time to stop relying on prescriptive drugs to alleviate all ailments and instead take charge of your own life wellness. He walks readers through the genes that are key to our physical and mental fitness and longevity, the genesis of those genes, and how actions play a role in the expression of genes in our bodies. Each chapter concludes with practical and easily implemented actions that help readers start managing their daily wellbeing and encourages them to personalize his steps for their own bodies and lifestyles. Dr. Paul has been recognized for his thought leadership, compassion, and entrepreneurialism. In addition to his busy skin surgery schedule, he offers 7,000 free skin cancer checks every year and even invented a skin graft technique that reduces costs and healing time for patients. With The Genetics of Health, he offers the knowledge and the guidance for readers to personally take charge of reducing their own healthcare costs and sick days, and to seize the healthiest life possible"--

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